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An Ichor-dependent apical extracellular matrix regulates seamless tube shape and integrity

During sprouting angiogenesis in the vertebrate vascular system, and primary branching in the Drosophila tracheal system, specialized tip cells direct branch outgrowth and network formation. When tip cells lumenize, they form subcellular (seamless) tubes. How these seamless tubes are made, shaped an...

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Detalles Bibliográficos
Publicado en:PLoS Genet
Autores principales: Rosa, Jeffrey B., Metzstein, Mark M., Ghabrial, Amin S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774827/
https://ncbi.nlm.nih.gov/pubmed/29309404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007146
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