An Ichor-dependent apical extracellular matrix regulates seamless tube shape and integrity

During sprouting angiogenesis in the vertebrate vascular system, and primary branching in the Drosophila tracheal system, specialized tip cells direct branch outgrowth and network formation. When tip cells lumenize, they form subcellular (seamless) tubes. How these seamless tubes are made, shaped an...

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Udgivet i:PLoS Genet
Main Authors: Rosa, Jeffrey B., Metzstein, Mark M., Ghabrial, Amin S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774827/
https://ncbi.nlm.nih.gov/pubmed/29309404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007146
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