Regulation of MEIS1 by Distal Enhancer Elements in Acute Leukemia

Aberrant activation of the three-amino-acid-loop extension (TALE) homeobox gene MEIS1 shortens the latency and accelerates the onset and progression of acute leukemia, yet the molecular mechanism underlying persistent activation of the MEIS1 gene in leukemia remains poorly understood. Here we used a...

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Bibliographic Details
Published in:Leukemia
Main Authors: Wang, Qian-fei, Li, Ya-jun, Dong, Jing-fang, Li, Bo, Kaberlein, Joseph J., Zhang, Lin, Arimura, Fábio Eiji, Luo, Roger T., Ni, Jun, He, Fuhong, Wu, Jun, Mattison, Ryan, Zhou, Jing, Wang, Chong-zhi, Prabhakar, Shyam, Nobrega, Marcelo A., Thirman, Michael J.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774621/
https://ncbi.nlm.nih.gov/pubmed/24022755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.260
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