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ER alpha binding by transcription factors NFIB and YBX1 enables FGFR2 signalling to modulate estrogen responsiveness in breast cancer

Two opposing clusters of transcription factors (TFs) have been associated with the differential risks of estrogen receptor positive or negative breast cancers, but the mechanisms underlying the opposing functions of the two clusters are undefined. In this study, we identified NFIB and YBX1 as novel...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Res
Hauptverfasser: Campbell, Thomas M., Castro, Mauro A. A., Gonçalves de Oliveira, Kelin, Ponder, Bruce A. J., Meyer, Kerstin B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774586/
https://ncbi.nlm.nih.gov/pubmed/29180470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1153
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