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ER alpha binding by transcription factors NFIB and YBX1 enables FGFR2 signalling to modulate estrogen responsiveness in breast cancer

Two opposing clusters of transcription factors (TFs) have been associated with the differential risks of estrogen receptor positive or negative breast cancers, but the mechanisms underlying the opposing functions of the two clusters are undefined. In this study, we identified NFIB and YBX1 as novel...

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Vydáno v:Cancer Res
Hlavní autoři: Campbell, Thomas M., Castro, Mauro A. A., Gonçalves de Oliveira, Kelin, Ponder, Bruce A. J., Meyer, Kerstin B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774586/
https://ncbi.nlm.nih.gov/pubmed/29180470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1153
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