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Epidermal growth factor receptor aptamer-conjugated polymer-lipid hybrid nanoparticles enhance salinomycin delivery to osteosarcoma and cancer stem cells

Osteosarcoma is a common childhood bone cancer with a poor survival rate. Osteosarcoma cancer stem cells (CSCs) contribute to the recurrence, drug resistance and metastasis of this disease. Previous evidence suggested that cancer cells are able to spontaneously turn into CSCs, thus it is crucial to...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Yu, Zuochong, Chen, Fangyi, Qi, Xiaoxia, Dong, Yinmei, Zhang, Yingying, Ge, Zhe, Cai, Guoping, Zhang, Xinchao
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774535/
https://ncbi.nlm.nih.gov/pubmed/29399118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5578
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