Salinomycin-loaded lipid-polymer nanoparticles with anti-CD20 aptamers selectively suppress human CD20+ melanoma stem cells

Melanoma is the deadliest type of skin cancer. CD20+ melanoma stem cells (CSCs) are pivotal for metastasis and initiation of melanoma. Therefore, selective elimination of CD20+ melanoma CSCs represents an effective treatment to eradicate melanoma. Salinomycin has emerged as an effective drug toward...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Zeng, Yi-bin, Yu, Zuo-chong, He, Yan-ni, Zhang, Tong, Du, Ling-bo, Dong, Yin-mei, Chen, Huai-wen, Zhang, Ying-ying, Wang, Wu-qing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800465/
https://ncbi.nlm.nih.gov/pubmed/29388568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.166
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