Trabodenoson, an Adenosine Mimetic With A(1) Receptor Selectivity Lowers Intraocular Pressure by Increasing Conventional Outflow Facility in Mice

PURPOSE: To evaluate the relationship between the IOP-lowering effect of trabodenoson and the associated structural and functional changes in the trabecular meshwork (TM). METHODS: Six independent cohorts of young and aged mice were exposed to three different topical once-a-day formulations of trabo...

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Veröffentlicht in:Invest Ophthalmol Vis Sci
Hauptverfasser: Li, Guorong, Torrejon, Karen Y., Unser, Andrea M., Ahmed, Feryan, Navarro, Iris D., Baumgartner, Rudolf A., Albers, David S., Stamer, W. Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2018
Schlagworte:
Physiology and Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774255/
https://ncbi.nlm.nih.gov/pubmed/29346804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-23212
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