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Regadenoson, a Novel Pharmacologic Stress Agent for Use in Myocardial Perfusion Imaging, Does Not Have a Direct Effect on the QT Interval in Conscious Dogs

Our goal was to determine the effect of regadenoson (a novel A(2A) adenosine receptor agonist) on the QT interval in conscious dogs. Eleven mongrel dogs were chronically instrumented for measurements of blood pressure and ECG. Regadenoson (2.5, 5 and 10 μg/kg, IV) caused a dose-dependent QT interval...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cardiovasc Pharmacol
Hauptverfasser: Zhao, Gong, Serpllion, Sabrina, Shryock, John, Messina, Eric, Xu, Xiaobin, Ochoa, Manuel, Belardinelli, Luiz, Hintze, Thomas H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774219/
https://ncbi.nlm.nih.gov/pubmed/19033827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e31818e035b
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