RNA‐Peptide nanoplexes drug DNA damage pathways in high‐grade serous ovarian tumors

DNA damaging chemotherapy is a cornerstone of current front‐line treatments for advanced ovarian cancer (OC). Despite the fact that a majority of these patients initially respond to therapy, most will relapse with chemo‐resistant disease; therefore, adjuvant treatments that synergize with DNA‐damagi...

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Pubblicato in:Bioeng Transl Med
Autori principali: Dreaden, Erik C., Kong, Yi Wen, Quadir, Mohiuddin A., Correa, Santiago, Suárez‐López, Lucia, Barberio, Antonio E., Hwang, Mun Kyung, Shi, Aria C., Oberlton, Benjamin, Gallagher, Paige N., Shopsowitz, Kevin E., Elias, Kevin M., Yaffe, Michael B., Hammond, Paula T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Research Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773954/
https://ncbi.nlm.nih.gov/pubmed/29376131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btm2.10086
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