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Ligand-decorated click polypeptide derived nanoparticles for targeted drug delivery applications

A ligand decorated, synthetic polypeptide block copolymer platform with environment-responsive capabilities was designed. We evaluated the potential of this system to function as a polymersome for targeted-delivery of a systemic chemotherapy to tumors. Our system employed click chemistry to provide...

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Publicado en:Nanomedicine
Autores principales: Quadir, Mohiuddin A., Morton, Stephen W., Mensah, Lawrence B., Shopsowitz, Kevin, Dobbelaar, Jeroen, Effenberger, Nicole, Hammond, Paula T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641973/
https://ncbi.nlm.nih.gov/pubmed/28263813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2017.02.010
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