Activation of Ca(2+)-sensing receptor as a protective pathway to reduce Cadmium-induced cytotoxicity in renal proximal tubular cells

Cadmium (Cd), as an extremely toxic metal could accumulate in kidney and induce renal injury. Previous studies have proved that Cd impact on renal cell proliferation, autophagy and apoptosis, but the detoxification drugs and the functional mechanism are still in study. In this study, we used mouse r...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Gu, Jie, Dai, Shuya, Liu, Yanmin, Liu, Haitao, Zhang, Yao, Ji, Xingqi, Yu, Feng, Zhou, Yang, Chen, Liang, Tse, William Ka Fai, Wong, Chris Kong Chu, Chen, Binghai, Shi, Haifeng
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773512/
https://ncbi.nlm.nih.gov/pubmed/29348484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19327-9
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