Activation of Ca(2+)-sensing receptor as a protective pathway to reduce Cadmium-induced cytotoxicity in renal proximal tubular cells

Cadmium (Cd), as an extremely toxic metal could accumulate in kidney and induce renal injury. Previous studies have proved that Cd impact on renal cell proliferation, autophagy and apoptosis, but the detoxification drugs and the functional mechanism are still in study. In this study, we used mouse r...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gu, Jie, Dai, Shuya, Liu, Yanmin, Liu, Haitao, Zhang, Yao, Ji, Xingqi, Yu, Feng, Zhou, Yang, Chen, Liang, Tse, William Ka Fai, Wong, Chris Kong Chu, Chen, Binghai, Shi, Haifeng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773512/
https://ncbi.nlm.nih.gov/pubmed/29348484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19327-9
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