A phase I/II randomized trial of clofarabine or fludarabine added to idarubicin and cytarabine for adults with relapsed or refractory acute myeloid leukemia

The purine nucleoside analogues clofarabine and fludarabine are active in acute myeloid leukemia (AML). We conducted a phase I/II randomized study of idarubicin and cytarabine with either clofarabine (CIA) or fludarabine (FIA) for relapsed or refractory AML. Clofarabine 15 mg/m(2) was identified as...

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Publicat a:Leuk Lymphoma
Autors principals: Short, Nicholas J., Kantarjian, Hagop, Ravandi, Farhad, Huang, Xuelin, Xiao, Lianchun, Garcia-Manero, Guillermo, Plunkett, William, Gandhi, Varsha, Sasaki, Koji, Pemmaraju, Naveen, Daver, Naval G., Borthakur, Gautam, Jain, Nitin, Konopleva, Marina, Estrov, Zeev, Kadia, Tapan M., Wierda, William G., DiNardo, Courtney D., Brandt, Mark, O’Brien, Susan M., Cortes, Jorge E., Jabbour, Elias
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773400/
https://ncbi.nlm.nih.gov/pubmed/28718728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2017.1349907
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