A phase I/II randomized trial of clofarabine or fludarabine added to idarubicin and cytarabine for adults with relapsed or refractory acute myeloid leukemia

The purine nucleoside analogues clofarabine and fludarabine are active in acute myeloid leukemia (AML). We conducted a phase I/II randomized study of idarubicin and cytarabine with either clofarabine (CIA) or fludarabine (FIA) for relapsed or refractory AML. Clofarabine 15 mg/m(2) was identified as...

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Veröffentlicht in:Leuk Lymphoma
Hauptverfasser: Short, Nicholas J., Kantarjian, Hagop, Ravandi, Farhad, Huang, Xuelin, Xiao, Lianchun, Garcia-Manero, Guillermo, Plunkett, William, Gandhi, Varsha, Sasaki, Koji, Pemmaraju, Naveen, Daver, Naval G., Borthakur, Gautam, Jain, Nitin, Konopleva, Marina, Estrov, Zeev, Kadia, Tapan M., Wierda, William G., DiNardo, Courtney D., Brandt, Mark, O’Brien, Susan M., Cortes, Jorge E., Jabbour, Elias
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773400/
https://ncbi.nlm.nih.gov/pubmed/28718728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2017.1349907
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