A phase I/II randomized trial of clofarabine or fludarabine added to idarubicin and cytarabine for adults with relapsed or refractory acute myeloid leukemia

The purine nucleoside analogues clofarabine and fludarabine are active in acute myeloid leukemia (AML). We conducted a phase I/II randomized study of idarubicin and cytarabine with either clofarabine (CIA) or fludarabine (FIA) for relapsed or refractory AML. Clofarabine 15 mg/m(2) was identified as...

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Опубликовано в: :Leuk Lymphoma
Главные авторы: Short, Nicholas J., Kantarjian, Hagop, Ravandi, Farhad, Huang, Xuelin, Xiao, Lianchun, Garcia-Manero, Guillermo, Plunkett, William, Gandhi, Varsha, Sasaki, Koji, Pemmaraju, Naveen, Daver, Naval G., Borthakur, Gautam, Jain, Nitin, Konopleva, Marina, Estrov, Zeev, Kadia, Tapan M., Wierda, William G., DiNardo, Courtney D., Brandt, Mark, O’Brien, Susan M., Cortes, Jorge E., Jabbour, Elias
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773400/
https://ncbi.nlm.nih.gov/pubmed/28718728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2017.1349907
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