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The pore forming protein gasdermin D regulates interleukin-1 secretion from living macrophages

The Interleukin-1 (IL-1) family cytokines are cytosolic proteins that exhibit inflammatory activity upon release into the extracellular space. These factors are released following various cell death processes, with pyroptosis being a common mechanism. Recently, it was recognized that phagocytes can...

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Bibliografische gegevens
Gepubliceerd in:Immunity
Hoofdauteurs: Evavold, Charles L., Ruan, Jianbin, Tan, Yunhao, Xia, Shiyu, Wu, Hao, Kagan, Jonathan C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773350/
https://ncbi.nlm.nih.gov/pubmed/29195811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.11.013
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