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Computational study of HIV gp120 as a target for polyanionic entry inhibitors: Exploiting the V3 loop region

Multiple approaches are being utilized to develop therapeutics to treat HIV infection. One approach is designed to inhibit entry of HIV into host cells, with a target being the viral envelope glycoprotein, gp120. Polyanionic compounds have been shown to be effective in inhibiting HIV entry, with a m...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hollingsworth, Louis R., Brown, Anne M., Gandour, Richard D., Bevan, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773097/
https://ncbi.nlm.nih.gov/pubmed/29346393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190658
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