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AMP Kinase Promotes Bcl6 Expression in both Mouse and Human T cells

The transcription factor Bcl6 is a master regulator of follicular helper T (T(FH)) cells, and understanding the signaling pathway that induces Bcl6 and T(FH) cell differentiation is therefore critical. IL-2 produced during T cell activation inhibits Bcl6 expression but how T(FH) cells evade IL-2 inh...

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Detalhes bibliográficos
Publicado no:Mol Immunol
Main Authors: Xie, Markus M., Amet, Tohti, Liu, Hong, Yu, Qigui, Dent, Alexander L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772768/
https://ncbi.nlm.nih.gov/pubmed/27898346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2016.11.020
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