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Role of the Cyclic AMP Response Element in the bcl-2 Promoter in the Regulation of Endogenous Bcl-2 Expression and Apoptosis in Murine B Cells

We have previously shown for B-cell lines that the cyclic AMP response element (CRE) is a major positive regulatory site in the bcl-2 promoter. However, the role of the CRE in the regulation of endogenous bcl-2 expression in vivo has not been characterized. We used gene targeting to generate knock-i...

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Sonraí Bibleagrafaíochta
Main Authors: Xiang, Hong, Wang, Jinghong, Boxer, Linda M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636799/
https://ncbi.nlm.nih.gov/pubmed/16982684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01062-06
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