Wird geladen...

α-Synuclein may cross-bridge v-SNARE and acidic phospholipids to facilitate SNARE-dependent vesicle docking

Misfolded α-synuclein (A-syn) is widely recognized as the primal cause of neurodegenerative diseases including Parkinson’s disease and dementia with Lewy bodies. The normal cellular function of A-syn has, however, been elusive. There is evidence that A-syn plays multiple roles in the exocytotic path...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biochem J
Hauptverfasser: Lou, Xiaochu, Kim, Jaewook, Hawk, Brenden J., Shin, Yeon-Kyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772654/
https://ncbi.nlm.nih.gov/pubmed/28495859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170200
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!