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Differential tissue specific, temporal and spatial expression patterns of the Aggrecan gene is modulated by independent enhancer elements

The transcriptional mechanism through which chondrocytes control the spatial and temporal composition of the cartilage tissue has remained largely elusive. The central aim of this study was to identify whether transcriptional enhancers played a role in the organisation of the chondrocytes in cartila...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Li, Ian M. H., Liu, Ke, Neal, Alice, Clegg, Peter D., De Val, Sarah, Bou-Gharios, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772622/
https://ncbi.nlm.nih.gov/pubmed/29343853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19186-4
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