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Differential tissue specific, temporal and spatial expression patterns of the Aggrecan gene is modulated by independent enhancer elements

The transcriptional mechanism through which chondrocytes control the spatial and temporal composition of the cartilage tissue has remained largely elusive. The central aim of this study was to identify whether transcriptional enhancers played a role in the organisation of the chondrocytes in cartila...

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Publicado en:Sci Rep
Main Authors: Li, Ian M. H., Liu, Ke, Neal, Alice, Clegg, Peter D., De Val, Sarah, Bou-Gharios, George
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772622/
https://ncbi.nlm.nih.gov/pubmed/29343853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19186-4
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