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Differential tissue specific, temporal and spatial expression patterns of the Aggrecan gene is modulated by independent enhancer elements

The transcriptional mechanism through which chondrocytes control the spatial and temporal composition of the cartilage tissue has remained largely elusive. The central aim of this study was to identify whether transcriptional enhancers played a role in the organisation of the chondrocytes in cartila...

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Pubblicato in:Sci Rep
Autori principali: Li, Ian M. H., Liu, Ke, Neal, Alice, Clegg, Peter D., De Val, Sarah, Bou-Gharios, George
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772622/
https://ncbi.nlm.nih.gov/pubmed/29343853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19186-4
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