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Structural and functional insights into S-thiolation of human serum albumins

Human serum albumin (HSA) is the most abundant serum protein, contributing to the maintenance of redox balance in the extracellular fluids. One single free cysteine residue at position 34 is believed to be a target of oxidation. However, the molecular details and functions of oxidized HSAs remain ob...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Nakashima, Fumie, Shibata, Takahiro, Kamiya, Kohei, Yoshitake, Jun, Kikuchi, Ryosuke, Matsushita, Tadashi, Ishii, Isao, Giménez-Bastida, Juan A., Schneider, Claus, Uchida, Koji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772555/
https://ncbi.nlm.nih.gov/pubmed/29343798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19610-9
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