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Oxidative metabolism of curcumin-glucuronide by peroxidases and isolated human leukocytes

Conjugation with glucuronic acid is a prevalent metabolic pathway of orally administrated curcumin, the bioactive diphenol of the spice turmeric. The major in vitro degradation reaction of curcumin is autoxidative transformation resulting in oxygenation and cyclization of the heptadienedione chain t...

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Bibliografiske detaljer
Udgivet i:Biochem Pharmacol
Main Authors: Luis, Paula B., Gordon, Odaine N., Nakashima, Fumie, Joseph, Akil I., Shibata, Takahiro, Uchida, Koji, Schneider, Claus
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390522/
https://ncbi.nlm.nih.gov/pubmed/28274615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.03.002
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