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HER2-driven Breast Tumorigenesis Relies upon Interactions of the Estrogen Receptor with Coactivator MED1

Studies of the estrogen receptor (ER) coactivator protein MED1 have revealed its specific roles in pubertal mammary gland development and potential contributions to breast tumorigenesis, based on co-amplification of MED1 and HER2 in certain breast cancers. In this study, we generated a mouse model o...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Yang, Yongguang, Leonard, Marissa, Zhang, Yijuan, Zhao, Dan, Mahmoud, Charif, Khan, Shugufta, Wang, Jiang, Lower, Elyse E., Zhang, Xiaoting
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771879/
https://ncbi.nlm.nih.gov/pubmed/29187405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1533
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