Overcoming Tamoxifen Resistance of Human Breast Cancer by Targeted Gene Silencing Using Multifunctional pRNA Nanoparticles

Most breast cancers express estrogen receptor (ER) α, and the antiestrogen drug tamoxifen has been widely used for their treatment. Unfortunately, up to half of all ERα-positive tumors have intrinsic or acquired endocrine therapy resistance. Our recent studies revealed that the ER coactivator Mediat...

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Detaylı Bibliyografya
Yayımlandı:ACS Nano
Asıl Yazarlar: Zhang, Yijuan, Leonard, Marissa, Shu, Yi, Yang, Yongguang, Shu, Dan, Guo, Peixuan, Zhang, Xiaoting
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488869/
https://ncbi.nlm.nih.gov/pubmed/27966906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.6b05910
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