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Assembly of Therapeutic pRNA-siRNA Nanoparticles Using Bipartite Approach
The 117-nucleotide (nt) RNA, called the packaging RNA (pRNA) of bacteriophage phi29 DNA packaging motor, has been shown to be an efficient vector for the construction of RNA nanoparticles for the delivery of small interfering RNA (siRNA) into specific cancer or viral-infected cells. Currently, chemi...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129561/ https://ncbi.nlm.nih.gov/pubmed/21468002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.23 |
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