Assembly of Therapeutic pRNA-siRNA Nanoparticles Using Bipartite Approach

The 117-nucleotide (nt) RNA, called the packaging RNA (pRNA) of bacteriophage phi29 DNA packaging motor, has been shown to be an efficient vector for the construction of RNA nanoparticles for the delivery of small interfering RNA (siRNA) into specific cancer or viral-infected cells. Currently, chemi...

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Bibliografiska uppgifter
Huvudupphovsmän: Shu, Yi, Cinier, Mathieu, Fox, Sejal R, Ben-Johnathan, Nira, Guo, Peixuan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2011
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129561/
https://ncbi.nlm.nih.gov/pubmed/21468002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.23
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