Assembly of Therapeutic pRNA-siRNA Nanoparticles Using Bipartite Approach

The 117-nucleotide (nt) RNA, called the packaging RNA (pRNA) of bacteriophage phi29 DNA packaging motor, has been shown to be an efficient vector for the construction of RNA nanoparticles for the delivery of small interfering RNA (siRNA) into specific cancer or viral-infected cells. Currently, chemi...

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Bibliografiske detaljer
Main Authors: Shu, Yi, Cinier, Mathieu, Fox, Sejal R, Ben-Johnathan, Nira, Guo, Peixuan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129561/
https://ncbi.nlm.nih.gov/pubmed/21468002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.23
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