Assembly of Therapeutic pRNA-siRNA Nanoparticles Using Bipartite Approach

The 117-nucleotide (nt) RNA, called the packaging RNA (pRNA) of bacteriophage phi29 DNA packaging motor, has been shown to be an efficient vector for the construction of RNA nanoparticles for the delivery of small interfering RNA (siRNA) into specific cancer or viral-infected cells. Currently, chemi...

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Hlavní autoři: Shu, Yi, Cinier, Mathieu, Fox, Sejal R, Ben-Johnathan, Nira, Guo, Peixuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129561/
https://ncbi.nlm.nih.gov/pubmed/21468002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.23
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