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Fabrication of Polyvalent Therapeutic RNA Nanoparticles for Specific Delivery of siRNA, Ribozyme and Drugs to Targeted Cells for Cancer Therapy

Bacteriophage phi29 DNA packaging motor is geared by a six-pRNA ring. pRNA is able to form a multimeric complex and patterned superstructures via the interaction of two reengineered interlocking loops. This unique feature makes it an ideal polyvalent vehicle for nanomachine fabrication, pathogen det...

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Hlavní autoři: Shu, Yi, Shu, Dan, Diao, Zhijuan, Shen, Guanxin, Guo, Peixuan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019567/
https://ncbi.nlm.nih.gov/pubmed/21243099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/LISSA.2009.4906696
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