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Ocular Delivery of pRNA Nanoparticles: Distribution and Clearance After Subconjunctival Injection

PURPOSE: RNA nanoparticles derived from the three-way junction (3WJ) of the pRNA of bacteriophage phi29 DNA packaging motor were previously found to be thermodynamically stable. As the nanoparticles could have potential in ocular drug delivery, the objectives in the present study were to investigate...

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Detalhes bibliográficos
Main Authors: Feng, Liang, Li, S. Kevin, Liu, Hongshan, Liu, Chia-Yang, LaSance, Kathleen, Haque, Farzin, Shu, Dan, Guo, Peixuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124000/
https://ncbi.nlm.nih.gov/pubmed/24297069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1226-x
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