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Ocular Delivery of pRNA Nanoparticles: Distribution and Clearance After Subconjunctival Injection

PURPOSE: RNA nanoparticles derived from the three-way junction (3WJ) of the pRNA of bacteriophage phi29 DNA packaging motor were previously found to be thermodynamically stable. As the nanoparticles could have potential in ocular drug delivery, the objectives in the present study were to investigate...

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Bibliografske podrobnosti
Main Authors: Feng, Liang, Li, S. Kevin, Liu, Hongshan, Liu, Chia-Yang, LaSance, Kathleen, Haque, Farzin, Shu, Dan, Guo, Peixuan
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124000/
https://ncbi.nlm.nih.gov/pubmed/24297069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1226-x
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