Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis

BACKGROUND: Cystic fibrosis (CF) lung disease is defined by large numbers of neutrophils and associated damaging products in the airway. Delayed neutrophil apoptosis is described in CF although it is unclear whether this is a primary neutrophil defect or a response to chronic inflammation. Increased...

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Detalles Bibliográficos
Publicado en:Thorax
Main Authors: Gray, Robert D, Hardisty, Gareth, Regan, Kate H, Smith, Maeve, Robb, Calum T, Duffin, Rodger, Mackellar, Annie, Felton, Jennifer M, Paemka, Lily, McCullagh, Brian N, Lucas, Christopher D, Dorward, David A, McKone, Edward F, Cooke, Gordon, Donnelly, Seamas C, Singh, Pradeep K, Stoltz, David A, Haslett, Christopher, McCray, Paul B, Whyte, Moira K B, Rossi, Adriano G, Davidson, Donald J
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2018
Assuntos:
Cystic Fibrosis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771859/
https://ncbi.nlm.nih.gov/pubmed/28916704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2017-210134
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