Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis

BACKGROUND: Cystic fibrosis (CF) lung disease is defined by large numbers of neutrophils and associated damaging products in the airway. Delayed neutrophil apoptosis is described in CF although it is unclear whether this is a primary neutrophil defect or a response to chronic inflammation. Increased...

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Detalhes bibliográficos
Publicado no:Thorax
Main Authors: Gray, Robert D, Hardisty, Gareth, Regan, Kate H, Smith, Maeve, Robb, Calum T, Duffin, Rodger, Mackellar, Annie, Felton, Jennifer M, Paemka, Lily, McCullagh, Brian N, Lucas, Christopher D, Dorward, David A, McKone, Edward F, Cooke, Gordon, Donnelly, Seamas C, Singh, Pradeep K, Stoltz, David A, Haslett, Christopher, McCray, Paul B, Whyte, Moira K B, Rossi, Adriano G, Davidson, Donald J
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Cystic Fibrosis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771859/
https://ncbi.nlm.nih.gov/pubmed/28916704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2017-210134
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