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Glycosylphosphatidylinositol (GPI) Anchored Protein Deficiency Serves as a Reliable Reporter of Pig-a Gene Mutation—Support from an In vitro Assay Based on L5178Y/Tk(+/−) Cells and the CD90.2 Antigen
Lack of cell surface glycosylphosphatidylinositol (GPI)-anchored protein(s) has been used as a reporter of Pig-a gene mutation in several model systems. As an extension of this work, our laboratory initiated development of an in vitro mutation assay based on the flow cytometric assessment of CD90.2...
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| Publicado en: | Environ Mol Mutagen |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5771857/ https://ncbi.nlm.nih.gov/pubmed/29115020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22154 |
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