Glycosylphosphatidylinositol (GPI)-deficient Jurkat T cells as a model to study functions of GPI-anchored proteins

Many cell surface proteins attached to the membrane by GPI are involved in cell signalling. However, the role of the GPI membrane anchor itself remains poorly understood. GPI-defective cells from patients with paroxysmal nocturnal haemoglobinuria (PNH) are relatively resistant to apoptosis induction...

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Detalhes bibliográficos
Main Authors: Bastisch, I, Tiede, A, Deckert, M, Ziolek, A, Schmidt, R E, Schubert, J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Human Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905750/
https://ncbi.nlm.nih.gov/pubmed/11012617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01350.x
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