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RFT1 Protein Affects Glycosylphosphatidylinositol (GPI) Anchor Glycosylation

The membrane protein RFT1 is essential for normal protein N-glycosylation, but its precise function is not known. RFT1 was originally proposed to translocate the glycolipid Man(5)GlcNAc(2)-PP-dolichol (needed to synthesize N-glycan precursors) across the endoplasmic reticulum membrane, but subsequen...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gottier, Petra, Gonzalez-Salgado, Amaia, Menon, Anant K., Liu, Yuk-Chien, Acosta-Serrano, Alvaro, Bütikofer, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247644/
https://ncbi.nlm.nih.gov/pubmed/27927990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.758367
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