Human and mouse Gpi1p homologues restore glycosylphosphatidylinositol membrane anchor biosynthesis in yeast mutants.

Glycosylphosphatidylinositol (GPI) represents an important anchoring molecule for cell surface proteins. The first step in its synthesis is the transfer of N-acetylglucosamine (GlcNAc) from UDP to phosphatidylinositol (PI). The products of three mammalian genes, PIG-A, PIG-C and PIG-H, have previous...

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Main Authors: Tiede, A, Schubert, J, Nischan, C, Jensen, I, Westfall, B, Taron, C H, Orlean, P, Schmidt, R E
Formato: Artigo
Idioma:Inglês
Publicado: 1998
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219730/
https://ncbi.nlm.nih.gov/pubmed/9729469
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