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Glycosylphosphatidylinositol Biosynthesis Defects in Gpi11p- and Gpi13p-deficient Yeast Suggest a Branched Pathway and Implicate Gpi13p in Phosphoethanolamine Transfer to the Third Mannose

Glycosylphosphatidylinositols (GPIs) are critical for membrane anchoring and intracellular transport of certain secretory proteins. GPIs have a conserved trimannosyl core bearing a phosphoethanolamine (EthN-P) moiety on the third mannose (Man-3) through which the glycolipid is linked to protein, but...

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Detalhes bibliográficos
Main Authors: Taron, Christopher H., Wiedman, Jill M., Grimme, Stephen J., Orlean, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14871/
https://ncbi.nlm.nih.gov/pubmed/10793139
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