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Five criteria for using a surrogate endpoint to predict treatment effect based on data from multiple previous trials
A surrogate endpoint in a randomized clinical trial is an endpoint that occurs after randomization and before the true, clinically meaningful, endpoint that yields conclusions about the effect of treatment on true endpoint. A surrogate endpoint can accelerate the evaluation of new treatments but at...
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| Publicado en: | Stat Med |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5771803/ https://ncbi.nlm.nih.gov/pubmed/29164641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7561 |
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