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Surrogate Endpoint Analysis: An Exercise in Extrapolation
Surrogate endpoints offer the hope of smaller or shorter cancer trials. It is, however, important to realize they come at the cost of an unverifiable extrapolation that could lead to misleading conclusions. With cancer prevention, the focus is on hypothesis testing in small surrogate endpoint trials...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3611854/ https://ncbi.nlm.nih.gov/pubmed/23264679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djs527 |
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