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Simple Methods for Evaluating 4 Types of Biomarkers: Surrogate Endpoint, Prognostic, Predictive, and Cancer Screening

We review simple methods for evaluating 4 types of biomarkers. First, we discuss the evaluation of surrogate endpoint biomarkers (to shorten a randomized trial) using 2 statistical and 3 biological criteria. Second, we discuss the evaluation of prognostic biomarkers (to predict the risk of disease)...

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Pubblicato in:Biomark Insights
Autori principali: Baker, Stuart G, Kramer, Barnett S
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7412628/
https://ncbi.nlm.nih.gov/pubmed/32821082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1177271920946715
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