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Regulation of Mitochondrial Biogenesis in Erythropoiesis by mTORC1-Mediated Protein Translation

Advances in genomic profiling present new challenges of explaining how changes in DNA and RNA are translated into proteins linking genotype to phenotype. Here we compare the genome-scale proteomic and transcriptomic changes in human primary hematopoietic stem/progenitor cells and erythroid progenito...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Cell Biol
Hauptverfasser: Liu, Xin, Zhang, Yuannyu, Ni, Min, Cao, Hui, Signer, Robert A.J., Li, Dan, Li, Mushan, Gu, Zhimin, Hu, Zeping, Dickerson, Kathryn E., Weinberg, Samuel E., Chandel, Navdeep S., DeBerardinis, Ralph J., Zhou, Feng, Shao, Zhen, Xu, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771482/
https://ncbi.nlm.nih.gov/pubmed/28504707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3527
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