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Regulation of Mitochondrial Biogenesis in Erythropoiesis by mTORC1-Mediated Protein Translation

Advances in genomic profiling present new challenges of explaining how changes in DNA and RNA are translated into proteins linking genotype to phenotype. Here we compare the genome-scale proteomic and transcriptomic changes in human primary hematopoietic stem/progenitor cells and erythroid progenito...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Liu, Xin, Zhang, Yuannyu, Ni, Min, Cao, Hui, Signer, Robert A.J., Li, Dan, Li, Mushan, Gu, Zhimin, Hu, Zeping, Dickerson, Kathryn E., Weinberg, Samuel E., Chandel, Navdeep S., DeBerardinis, Ralph J., Zhou, Feng, Shao, Zhen, Xu, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771482/
https://ncbi.nlm.nih.gov/pubmed/28504707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3527
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