A single nucleotide polymorphism in CYP1B1 leads to differential prostate cancer risk and telomere length

BACKGROUND: Cytochrome P450 1B1 (CYP1B1) is a key enzyme in its oestrogen metabolism pathway, giving rise to hydroxylation and conjugation. Functionally relevant genetic variants within CYP1B1 may affect the telomere length and subsequently lead to prostate carcinogenesis. METHODS: We evaluated 8 CY...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cancer
Main Authors: Gu, Cheng-Yuan, Li, Gao-Xiang, Zhu, Yu, Xu, Hua, Zhu, Yao, Qin, Xiao-Jian, Bo, Dai, Ye, Ding-Wei
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2018
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771334/
https://ncbi.nlm.nih.gov/pubmed/29344273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.21774
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