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A single nucleotide polymorphism in CYP1B1 leads to differential prostate cancer risk and telomere length
BACKGROUND: Cytochrome P450 1B1 (CYP1B1) is a key enzyme in its oestrogen metabolism pathway, giving rise to hydroxylation and conjugation. Functionally relevant genetic variants within CYP1B1 may affect the telomere length and subsequently lead to prostate carcinogenesis. METHODS: We evaluated 8 CY...
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| Publicado en: | J Cancer |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Ivyspring International Publisher
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5771334/ https://ncbi.nlm.nih.gov/pubmed/29344273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.21774 |
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