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Gremlin Regulates Podocyte Apoptosis via Transforming Growth Factor-β (TGF-β) Pathway in Diabetic Nephropathy

BACKGROUND: Gremlin has been reported to be up-regulated in glomerular mesangial cells in diabetic nephropathy (DN). However, the regulation of gremlin in podocytes is still rarely reported. This study aimed to investigate the underlying mechanisms by which gremlin mediates the pathogenesis of DN vi...

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Détails bibliographiques
Publié dans:Med Sci Monit
Auteurs principaux: Wang, Xiao-Bing, Zhu, Hong, Song, Wei, Su, Jian-Hua
Format: Artigo
Langue:Inglês
Publié: International Scientific Literature, Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771160/
https://ncbi.nlm.nih.gov/pubmed/29315280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.905758
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