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Long Non-Coding RNA (LncRNA)-ATB Promotes Inflammation, Cell Apoptosis and Senescence in Transforming Growth Factor-β1 (TGF-β1) Induced Human Kidney 2 (HK-2) Cells via TGFβ/SMAD2/3 Signaling Pathway

BACKGROUND: Renal fibrosis occurs in the end-stage of all chronic kidney disease. Transforming growth factor-β1 (TGF-β1) is a central contributor in fibrosis. Identifying effective biomarkers that targets TGF-β1 is necessary for the development of therapeutic agents for kidney disease. In this study...

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Publicado en:Med Sci Monit
Main Authors: Sun, Han, Ke, Cong, Zhang, Lin, Tian, Changjun, Zhang, Zhihui, Wu, Shuhua
Formato: Artigo
Idioma:Inglês
Publicado: International Scientific Literature, Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265746/
https://ncbi.nlm.nih.gov/pubmed/32447340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.922029
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