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Phosphorylation of the IDP KID Modulates Affinity for KIX by Increasing the Lifetime of the Complex

Intrinsically disordered proteins (IDPs) are known to undergo a range of posttranslational modifications, but by what mechanism do such modifications affect the binding of an IDP to its partner protein? We investigate this question using one such IDP, the kinase inducible domain (KID) of the transcr...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Dahal, Liza, Shammas, Sarah L., Clarke, Jane
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770967/
https://ncbi.nlm.nih.gov/pubmed/29262363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.10.015
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