Negative Effects of Chronic Rapamycin Treatment on Behavior in a Mouse Model of Fragile X Syndrome

Fragile X syndrome (FXS), the most common form of inherited intellectual disability, is also highly associated with autism spectrum disorders (ASD). It is caused by expansion of a CGG repeat sequence on the X chromosome resulting in silencing of the FMR1 gene. This is modeled in the mouse by deletio...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Mol Neurosci
Egile Nagusiak: Saré, Rachel M., Song, Alex, Loutaev, Inna, Cook, Anna, Maita, Isabella, Lemons, Abigail, Sheeler, Carrie, Smith, Carolyn B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2018
Gaiak:
Neuroscience
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770365/
https://ncbi.nlm.nih.gov/pubmed/29375310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00452
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