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Regional rates of brain protein synthesis are unaltered in dexmedetomidine sedated young men with fragile X syndrome: A L-[1-(11)C]leucine PET study

Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability. Fragile X mental retardation protein (FMRP), a putative translation suppressor, is absent or significantly reduced in FXS. One prevailing hypothesis is that rates of protein synthesis are increased by the absence...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Schmidt, Kathleen C., Loutaev, Inna, Quezado, Zenaide, Sheeler, Carrie, Smith, Carolyn Beebe
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425798/
https://ncbi.nlm.nih.gov/pubmed/32569795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.104978
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